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Preheat oven to 400°F. Line a baking sheet with parchment paper.
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Slice jalapeños in half lengthwise and remove seeds and membranes.
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Mix cream cheese, shredded cheese, garlic powder, onion powder, salt, and pepper.
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Fill each jalapeño half with the cheese mixture.
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Cut crescent dough into thin strips and wrap around each jalapeño, leaving an opening for the eyes.
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Place on the baking sheet.
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Whisk egg and water together and lightly brush the dough.
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Bake 12–15 minutes, until golden brown.
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Cool slightly and add candy eyes.
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Serve warm.